The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle through damage or overloading as such it can be caused by a wide number of conditions including myocardial infarction in which the heart muscle is starved of oxygen and dies hypertension which increases the force of contraction needed to pump blood and amyloidosis in which misfolded . Lef sided heart failure will not show peripheral edema activity intolerance hypoxia reduced pulse pressure reduced urine output from decreased blood flow to he major organs gut eschemia abdominal discomfort type of heart failure that is a life threatening condition in which the heart cannot pump enough blood to the body. This chapter deals with diseases of the heart with the following chapter focusing on diseases of the blood vessels normal cardiac structure and function are summarized here and pathophysiologic mechanisms for commonly encountered cardiac problems are then discussed with emphasis on arrhythmias heart failure valvular heart disease coronary . Fundamentals of pathophysiology disorders of heart failure jan 23 2020 posted by cao xueqin media text id 558b6a6e online pdf ebook epub library failure heart failure resulting in the accumulation of fluid in the lungs and other body tissues it is related mainly to salt and water retention in the tissues rather than directly. Heart failure results from injury to the myocardium from a variety of causes including ischemic heart disease hypertension and diabetes less common etiologies include cardiomyopathies valvular disease myocarditis infections systemic toxins and cardiotoxic drugs
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